Vaccines are just as important for indoor-only cats as they are for cats who have access to the outdoors.  Kittens are initially protected by maternal antibodies they receive when nursing.  By two months of age though,  these antibodies are gone.  Kittens are first given a Feline Distemper shot (FVRCP) which protects them against "rhinotracheitis",  "calicivirus" and "panleukopenia".  This shot must be boosted 3-4 weeks later by another dose of vaccine for full protection.  At four months of age,  a kitten receives it's first rabies vaccination.  This is always a one-year vaccine.  Even though a cat may never venture outside and be exposed to foxes and raccoons,  the chance of a bat entering your house or escaping outside accidentally is very real.  We at Cat Sense have actually had two bat incidents.  Rabies vaccinations are required by Maryland State Law and authorities do have the right to confiscate your cat should someone be bitten and vaccinations are not current.  Vaccinations for Feline Leukemia are not recommended unless your cat will be going outside and coming in contact with other cats or if you will be bringing new,  untested cats into the house.  A feline leukemia test should be performed prior to vaccination.